Fluocinolone Acetonide Impurity 27 CAS 3932-49-8
| CAS No. | 3932-49-8 |
| Molecular Formula | C26H34F2O7 |
| Molecular Weight | 496.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluocinolone Acetonide Impurity 27.
CATO supplies Fluocinolone Acetonide Impurity 27 (CAS 3932-49-8), a pharmacopoeial impurity reference standard (molecular formula C26H34F2O7, MW 496.54 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluocinolone Acetonide Impurity 27 (C26H34F2O7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluocinolone Acetonide Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H34F2O7 |
| Molecular Weight | 496.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide Impurity 23 (CAS CATO-C4X-238123)
- Fluocinolone Acetonide Impurity 32 (CAS 3914-23-6)
- Fluocinolone Acetonide Impurity 36 (CAS CATO-C4X-238136)
- Fluocinolone Acetonide EP Impurity M (CAS 356-12-7)
- Fluocinolone Acetonide Impurity 24 (CAS CATO-C4X-238124)
- Fluocinolone Acetonide Impurity 4 (CAS 62013-83-6)
- Fluocinolone Acetonide Impurity 37 (CAS CATO-C4X-238137)
- Fluocinolone Acetonide Impurity 15 (CAS 1181-32-4)
Recommended Standards
- 4,4',4''-((1S,3S,5S)-Adamantane-1,3,5-triyl)tribenzoic acid (CAS 160517-35-1)
- Ethyl 6-amino-5-cyano-2-[({5-cyano-[2,4'-bipyridine]-6-yl}sulfanyl)methyl]-4-(pyridin-3-yl)-4H-pyran-3-carboxylate (CAS 313380-23-3)
- (2R,3S,4R,5R,6S)-5-Amino-6-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-2-((R)-1-hydroxyethyl)tetrahydro-2H-pyran-3,4-diol (CAS 49863-47-0)
- 3-Amino-4-(4-methoxyphenyl)-N-(2-nitrophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332053-72-2)
- Econazole impurity 27 (CAS 27087-94-1)
- Imidafenacin Impurity 3 (CAS CATO-C4X-18083)
- Apixaban Impurity 67 (CAS 2323-81-1)
- Ziprasidone Related Compound F (CAS 1159977-64-6 (free base))
- 5-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1222533-84-7)
- 688-73-3 4XDX163P3D Tributyltin Tri-n-butyltin hydride Stannane, tributyl- Stannane, tri-n-butyl-, hydride Tributylstannane 4-04-00-04312 (Beilstein Handbook Reference) BRN 3587329 EINECS 211-704-4 HSDB 6362 Tin, tri-n-butyl-, hydride Tri-n-butylstannane hydride Tributylstannic hydride Tributyltin hydride Tributlytin UNII-4XDX163P3D (CAS 688-73-3)
- Methyl (2S,4S)-4-(4-propoxyphenoxy)-2-pyrrolidinecarboxylate hydrochloride (CAS 1354487-48-1)
- Methyl 3-(6-aminohexylcarbamoyl)benzoate (CAS 163755-54-2)
- 5-Acetyl-2-(4-bromophenoxy) pyridine (CAS 1557799-39-9)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com