2,4-dichloro-7-(trifluoromethyl)quinazoline CAS 396-02-1
| CAS No. | 396-02-1 |
| Molecular Formula | C9H13Cl2F3N2 |
| Molecular Weight | 277.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4-dichloro-7-(trifluoromethyl)quinazoline is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,4-dichloro-7-(trifluoromethyl)quinazoline (CAS 396-02-1), a certified reference material (molecular formula C9H13Cl2F3N2, MW 277.11 g/mol) for analytical method development and quality control.
The molecular framework of 2,4-dichloro-7-(trifluoromethyl)quinazoline (C9H13Cl2F3N2) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,4-dichloro-7-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13Cl2F3N2 |
| Molecular Weight | 277.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- N-(4-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 326901-97-7)
- 4-Bromo-3-nitropyridine hydrochloride (CAS 1260816-42-9)
- 2-(Benzylthio)-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1393544-29-0)
- rel-2-((1S,2S)-[1,1'-Bi(cyclopropan)]-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 350031-03-7)
- 5-(2-methylphenoxy)pyridine-2-carboxylic acid (CAS 1542935-15-8)
- Peptide Impurity 04 (CAS 2913424-91-4)
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