Tetracaine Impurity 18 CAS 398469-99-3
| CAS No. | 398469-99-3 |
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tetracaine Impurity 18 (CAS 398469-99-3), a pharmacopoeial impurity reference standard (molecular formula C16H25NO2, MW 263.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Tetracaine Impurity 18 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 263.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Tetracaine Standards
- Tetracaine Impurity 29 (CAS CATO-C4X-192329)
- Tetracaine (CAS 94-24-6)
- Tetracaine-d6 (CAS 756771-02-5)
- Tetracaine Impurity 31 (CAS CATO-C4X-192331)
- Tetracaine Impurity 39 (CAS 101265-45-6)
- Tetracaine Impurity 10 (CAS 65213-46-9)
- Tetracaine Impurity 14 (CAS 1029292-13-4)
- Tetracaine Impurity 6 (CAS 92726-05-1)
Recommended Standards
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- Dimetindene EP Impurity G (CAS 803617-18-7)
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- Triapenthenol (CAS 76608-88-3)
- Metoprolol Impurity 37 (CAS 488-17-5)
- henylephrine Impurity 42 (CAS 73898-35-8)
- Troxerutin Impurity 12 (CAS CATO-C4X-280012)
- Tert-butyl 4-((4-oxocyclohexyl)amino)piperidine-1-carboxylate (CAS 1824027-15-7)
- Upadacitinib Impurity 105 (CAS CATO-C4X-2405105)
- MADAM diHCl (CAS 411208-45-2)
- 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-hydrazino-N-(4-methylphenyl)-1,3,5-triazin-2-amine (CAS 1158287-77-4)
- Methyl 2,6-dibromo-3-methoxybenzoate (CAS 2383066-83-7)
- 25518-49-4 Isobutyryl-1-carnitine Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, isobutyrate, L- (S)-3-Carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxopropoxy)-1-propanaminium, hydroxide, inner salt 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxopropoxy)-, inner salt, (R)- (9CI) BRN 4138517 Iso-butyryl-L(-)-carnitin [German] Isobutyryl-carnitine Isobutyryl-L-carnitine Iso-butyryl-L(-)-carnitin (CAS 25518-49-4)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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