henylephrine Impurity 42 CAS 73898-35-8
| CAS No. | 73898-35-8 |
| Molecular Formula | C8H6Br2O2 |
| Molecular Weight | 293.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, henylephrine Impurity 42 (CAS 73898-35-8, C8H6Br2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, henylephrine Impurity 42 (C8H6Br2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 293.94 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), henylephrine Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Br2O2 |
| Molecular Weight | 293.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
Recommended Standards
- Dapagliflozin dibromide impurity (CAS 1043252-56-7)
- Phenylephrine Impurity 75 (CAS CATO-C4X-146775)
- 4-(Dibromomethyl)-benzoic Acid (CAS 29045-93-0)
- 4-(3,5-Dibromo-1H-1,2,4-triazol-1-yl)butanenitrile (CAS 1240572-96-6)
- Dexamethasone impurity 78 (CAS 1879-72-7)
- Tacrolimus EP Impurity G (CAS 144490-63-1)
- Ketoprofen Impurity 68 (CAS CATO-C4X-147168)
- 2-Chloro-4-methylbenzoxazole (CAS 1001185-81-4)
- N'-((6-(p-Tolyloxy)pyrimidin-4-yl)thio)acetohydrazide (CAS 137927-72-1)
- N-(4-Fluorophenyl)hydrazinecarbothioamide (CAS 330-94-9)
- 4-(4-(Pyrrolidin-1-yl)piperidin-1-yl)aniline (CAS 867291-46-1)
- 4-(2-Chlorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-87-9)
- (2S,4S)-1-(2-chloroacetyl)-4-fluoropyrrolidine-2-carbonitrile (CAS 596817-06-0)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com