1-(4-(Difluoromethoxy)phenyl)-3-(pyridin-3-ylmethyl)thiourea CAS 398995-91-0
| CAS No. | 398995-91-0 |
| Molecular Formula | C14H13F2N3OS |
| Molecular Weight | 309.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-(Difluoromethoxy)phenyl)-3-(pyridin-3-ylmethyl)thiourea (CAS 398995-91-0) is a high-purity analytical reference standard with the molecular formula C14H13F2N3OS and a molecular weight of 309.33 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-(Difluoromethoxy)phenyl)-3-(pyridin-3-ylmethyl)thiourea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-(Difluoromethoxy)phenyl)-3-(pyridin-3-ylmethyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13F2N3OS |
| Molecular Weight | 309.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (E)-5,5-dimethyl-3-(2-((4-(trifluoromethyl)phenyl)amino)vinyl)cyclohex-2-en-1-one (CAS 338759-35-6)
- 1-(Tert-butoxycarbonyl)-3-(2-fluorobenzyl)azetidine-3-carboxylic acid (CAS 2021921-92-4)
- (E)-5,5-dimethyl-3-(2-((3-(trifluoromethyl)phenyl)amino)vinyl)cyclohex-2-en-1-one (CAS 338759-32-3)
- 1-(Tert-butoxycarbonyl)-3-(3-fluorobenzyl)azetidine-3-carboxylic acid (CAS 2030113-39-2)
- 9-(sec-Butyl)acridine (CAS 16292-11-8)
- 3-Amino-2,6-dimethylpyridine (CAS 3430-33-9)
- 3-(4-Methylpiperazinomethyl)-4-thiomethylbenzophenone (CAS 898788-56-2)
- Padsevonil (CAS 1294000-61-5)
- Memantine Impurity N1(Mixture of Diastereomers) (CAS 16207-81-1)
- N,N'-(pentane-1,5-diyl)bis(5-(dimethylamino)naphthalene-1-sulfonamide) (CAS 55521-24-9)
- 5'-Bromo-[1,1':3',1''-terphenyl]-4,4''-diamine (CAS 2337335-29-0)
- (4-Fluoro-3-iodophenyl)(methyl)sulfane (CAS 2586126-82-9)
- H-Tyr-Ile-Tyr-Gly-Ser-Phe-Lys-OH (CAS 165190-42-1)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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