2-(2-Bromo-4-fluorophenoxy)acetic acid CAS 399-40-6
| CAS No. | 399-40-6 |
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(2-Bromo-4-fluorophenoxy)acetic acid (CAS 399-40-6), molecular formula C8H6BrFO3 and molecular weight 249.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-(2-Bromo-4-fluorophenoxy)acetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(2-Bromo-4-fluorophenoxy)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO3 |
| Molecular Weight | 249.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-4-fluoro-5-methoxybenzoic acid (CAS 1007455-21-1)
- Methyl 5-bromo-2-fluoro-4-hydroxybenzoate (CAS 1142227-35-7)
- Methyl 4-bromo-2-fluoro-6-hydroxybenzoate, 97% (CAS 1193162-18-3)
- Methyl 4-bromo-5-fluoro-2-hydroxybenzoate (CAS 1193162-25-2)
- 1-Bromo-2-ethynyl-4-(trifluoromethyl)benzene (CAS 1211523-00-0)
- 2-(3-Bromo-2-fluorophenyl)-2-hydroxyacetic acid (CAS 1214333-63-7)
- 2-(4-Bromo-3-fluorophenyl)-2-hydroxyacetic acid (CAS 1214333-66-0)
- 2-(2-Bromo-4-fluorophenyl)-2-hydroxyacetic acid (CAS 1214372-24-3)
Recommended Standards
- 1-(Bromoethynyl)-4-(trifluoromethyl)benzene (CAS 313343-88-3)
- 2-(2-Bromo-5-fluorophenoxy)acetic acid (CAS 874804-04-3)
- (4,8-Dimethoxy-2-oxo-1,2-dihydroquinolin-3-yl)boronic acid (CAS 202824-51-9)
- 2-(4-Bromo-2-fluorophenoxy)acetic acid (CAS 451-90-1)
- N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl Lansoprazole Sulfone (CAS 1391052-41-7)
- 4,5-Dichloro-6-(1-piperidinyl)pyrimidine (CAS 1823346-49-1)
- 2-(Aminomethyl)-5-cyano-3-(difluoromethyl)-6-methoxypyridine (CAS 1805286-56-9)
- 2-Methyl-3-(pyrrolidin-1-yl)propanoic acid hydrochloride (CAS 1365836-77-6)
- 1-(2-(3-Bromo-5-fluorophenoxy)ethyl)pyrrolidine (CAS 1516187-39-5)
- Methyl 4-(piperidin-1-yl)butanoate (CAS 63867-69-6)
- Bilastine impurity 80 (CAS 1789305-52-7)
- 2-(4-Formyl-6-hydroxypyridin-2-yl)acetic acid (CAS 1393539-89-3)
- 2-Fluoro-4-(4-formylphenyl)benzoic acid (CAS 1261970-90-4)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com