2-(2-Chloro-4-fluorophenoxy)acetic acid CAS 399-41-7
| CAS No. | 399-41-7 |
| Molecular Formula | C8H6ClFO3 |
| Molecular Weight | 204.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(2-Chloro-4-fluorophenoxy)acetic acid (CAS 399-41-7), a certified reference material (molecular formula C8H6ClFO3, MW 204.58 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Chloro-4-fluorophenoxy)acetic acid (C8H6ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2-Chloro-4-fluorophenoxy)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO3 |
| Molecular Weight | 204.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-4-fluoro-3-methoxybenzoic acid (CAS 1055968-55-2)
- 4-Chloro-2-fluoro-6-methoxybenzoic acid (CAS 1082042-25-8)
- 4-Chloro-2-fluoro-3-methoxybenzoic acid (CAS 1169870-80-7)
- 2-(2-Chloro-3-fluorophenyl)-2-hydroxyacetic acid (CAS 1214345-50-2)
- 4-Chloro-2-fluoromandelic Acid (CAS 1214345-56-8)
- 2-(5-Chloro-2-fluorophenyl)-2-hydroxyacetic acid (CAS 1214345-65-9)
- 2-(4-Chloro-3-fluorophenyl)-2-hydroxyacetic acid (CAS 1214376-99-4)
- 2-(3-Chloro-4-fluorophenyl)-2-hydroxyacetic acid (CAS 1214377-83-9)
Recommended Standards
- 1-Chloro-4-ethynyl-2-(trifluoromethyl)benzene (CAS 273928-28-2)
- 2-(2-Chloro-4-fluorophenyl)-2-hydroxyacetic acid (CAS 365525-72-0)
- 1-(4-Chlorophenyl)-3,3,3-trifluoropropyne (CAS 82203-84-7)
- 2-(3-Chloro-2-fluorophenoxy)acetic acid (CAS 447-49-4)
- Methyl nonacosanoate (CAS 4082-55-7)
- 4-chloro(3,6-²H₂)-1H-pyrazolo[3,4-d]pyrimidine (CAS 2891518-86-6)
- Tert-butyl (2-(hydroxymethyl)phenethyl)carbamate (CAS 1639885-09-8)
- 1-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1,4-diazepane (CAS 1094668-16-2)
- (6-Chloro-2-fluoro-3-methoxyphenyl)methanamine (CAS 1017779-65-5)
- (5S)-5-(((Tetrahydro-2H-pyran-2-yl)oxy)methyl)dihydrofuran-2(3H)-one (CAS 187264-97-7)
- n-(Piperidin-4-yl)-n-propylthiophene-2-carboxamide hydrochloride (CAS 1421604-90-1)
- 4,4-dimethyl-3,4-dihydro-2H-1-benzopyran (CAS 40614-27-5)
- Acotiamide Impurity 38 (CAS 877998-00-0)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com