2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-chlorophenyl)butanedinitrile CAS 400080-84-4
| CAS No. | 400080-84-4 |
| Molecular Formula | C16H8Cl2F3N3 |
| Molecular Weight | 370.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-chlorophenyl)butanedinitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-chlorophenyl)butanedinitrile (CAS 400080-84-4) is a high-purity analytical reference standard with the molecular formula C16H8Cl2F3N3 and a molecular weight of 370.16 g/mol.
2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-chlorophenyl)butanedinitrile (C16H8Cl2F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-chlorophenyl)butanedinitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F3N3 |
| Molecular Weight | 370.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- tert-Butyl 4-bromo-2-(trifluoromethoxy)benzylcarbamate (CAS 1241827-82-6)
- 3-((Tert-butoxycarbonyl)amino)-4-iodoisothiazole-5-carboxylic acid (CAS 2055841-49-9)
- 1-Methyl-2-(tri-n-butylstannyl)pyrrole,98% (CAS 118486-97-8)
- 3-(3-bromophenyl)-N-[3-(trifluoromethyl)phenyl]acrylamide (CAS 61592-74-3)
- 2-(Bromomethyl)-3-chloro-1,4-difluorobenzene 2-(bromomethyl)-3-chloro-1,4-difluorobenzene, alpha-bromo-2-chloro-3,6-difluorotoluene 2-chloro-3,6-difluorobenzyl bromide 2-chloro-3,6-difluorobenzyl bromide 97% 90292-67-4 alpha-bromo-2-chloro-3,6-difluorotoluene chloro-3,6-difluorobenzylbr currency-bromo-2-chloro-3,6-difluorotoluene (CAS 90292-67-4)
- 3,7-Dibromo-2,8-bis(octyloxy)dibenzo[b,d]furan (CAS 599212-92-7)
- H-Phe-Pro-Arg-OH (CAS 37553-80-3)
- 7-(4-Methoxyphenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477852-32-7)
- 4-Methyloxazole-2-carboxylic Acid (CAS 1196151-81-1)
- (1S,6R)-6-((tert-butoxycarbonyl)amino)cyclohex-3-ene-1-carboxylic acid (CAS 63216-52-4)
- 2-Chloro-4,6-dimethoxypyrimidine (CAS 13223-25-1)
- 2-[2-(dimethylamino)ethanesulfonyl]benzoic acid hydrochloride (CAS 1424128-65-3)
- (3-(N-cyclopentylsulfamoyl)-4-methylphenyl)boronic acid (CAS 1704095-47-5)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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