N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-N',2,6-trimethyl-4-oxo-1,4-dihydropyridine-3-carbohydrazide CAS 400082-52-2
| CAS No. | 400082-52-2 |
| Molecular Formula | C22H18Cl2F6N6O2 |
| Molecular Weight | 583.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 583.31 g/mol gives N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-N',2,6-trimethyl-4-oxo-1,4-dihydropyridine-3-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-N',2,6-trimethyl-4-oxo-1,4-dihydropyridine-3-carbohydrazide (CAS 400082-52-2), a certified reference material (molecular formula C22H18Cl2F6N6O2, MW 583.31 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-N',2,6-trimethyl-4-oxo-1,4-dihydropyridine-3-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 583.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18Cl2F6N6O2 |
| Molecular Weight | 583.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
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- tert-Butyl ((4-carbamoyloxazol-2-yl)methyl)carbamate (CAS 182120-97-4)
- 2-Bromo-4-(2-methoxy-4,5-dimethylphenyl)thiazole (CAS 1225790-45-3)
- (3-Bromo-4-methoxyphenyl)acetic Acid (CAS 774-81-2)
- 3-(Bromomethyl)-6-(difluoromethyl)-5-iodopyridin-2-amine (CAS 1806814-19-6)
- 2-Methyl-6-(2-phenylethynyl)pyridine (CAS 96206-92-7)
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- 5-ethyl-4-methylthiophene-2-carboxylic acid (CAS 40808-25-1)
- tert-Butyl 4,6-dichloro-2-(methylthio)pyrimidine-5-carboxylate (CAS 1192308-10-3)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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