1-[(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-N-[3-(propan-2-yloxy)phenyl]-1,2-dihydropyridine-3-carboxamide CAS 400083-07-0
| CAS No. | 400083-07-0 |
| Molecular Formula | C23H20F2N2O5 |
| Molecular Weight | 442.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-N-[3-(propan-2-yloxy)phenyl]-1,2-dihydropyridine-3-carboxamide.
1-[(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-N-[3-(propan-2-yloxy)phenyl]-1,2-dihydropyridine-3-carboxamide (CAS 400083-07-0) is a high-purity analytical reference standard with the molecular formula C23H20F2N2O5 and a molecular weight of 442.41 g/mol.
The molecular framework of 1-[(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-N-[3-(propan-2-yloxy)phenyl]-1,2-dihydropyridine-3-carboxamide (C23H20F2N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20F2N2O5 |
| Molecular Weight | 442.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
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Recommended Standards
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- 2-Methoxy-6-[2-(1,2,5-trimethyl-1H-pyrrol-3-yl)-vinyl]-benzoic acid methyl ester (CAS 365542-55-8)
- 2-[2-(Cbz-amino)phenyl]-1,3-dioxolane (CAS 1346597-58-7)
- 1-(3-fluorobenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 867329-86-0)
- 3-Methoxy-7,8-dihydroisoquinolin-5(6H)-one (CAS 209741-57-1)
- 4-(Furan-3-yl)butan-2-amine (CAS 1343694-40-5)
- Sucralose EP Impurity F (CAS 61854-83-9)
- 5,8-Dichloro-1,7-naphthyridine (CAS 67967-18-4)
- Benzene, [[(8-bromooctyl)oxy]methyl]- (CAS 83515-83-7)
- (R)-2-Amino-3-phenoxypropanoic acid (CAS 59123-23-8)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
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