2-(1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl)malononitrile CAS 400737-44-2
| CAS No. | 400737-44-2 |
| Molecular Formula | C16H10Cl2N2OS |
| Molecular Weight | 349.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl)malononitrile (CAS 400737-44-2), molecular formula C16H10Cl2N2OS and molecular weight 349.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl)malononitrile (C16H10Cl2N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-(1-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propyl)malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2N2OS |
| Molecular Weight | 349.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-(((3R,4R)-3,4-Dihydroxy-2-oxo-5-(phosphonooxy)pentyl)amino)benzoic acid (CAS 5962-18-5)
- 2,2-Difluoro-2-(4-fluorophenoxy)-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 338792-39-5)
- 1-Methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-benzo[d]imidazol-2-amine (CAS 330793-28-7)
- 2,2-Difluoro-N-(2-fluorophenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-22-6)
- 7,8-Dimethyl-2-(2-thienyl)quinoline-4-carbonyl chloride (CAS 1160261-38-0)
- (5-Bromo-1,3-phenylene)bis(trimethylsilane) (CAS 81500-92-7)
- Methyl 2-amino-5-methoxy-3-methylbenzoate (CAS 1007113-24-7)
- 2,3-Quinoxalinedione, 1,4-dihydro-1-methyl- (6CI,7CI,9CI) 20934-51-4 (CAS 20934-51-4)
- 6-Bromo-2H-oxazolo[3,2-a]pyrimidin-7(3H)-one (CAS 103022-66-8)
- 1-(2-Hydroxy-3-methylphenyl)propan-1-one (CAS 3338-15-6)
- 2-Chloro-3,4-difluorobenzoic Acid (CAS 150444-93-2)
- 3-(2-Chloro-4-fluorophenyl)-2-methyl-1-propene (CAS 951894-45-4)
- n-Ethyl-1-methyl-1h-imidazole-4-sulfonamide (CAS 1247098-03-8)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
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