Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate CAS 401566-70-9

Purity 97%+In StockPharmaceutical Standards
CAS No.401566-70-9
Molecular FormulaC12H16ClN3O2
Molecular Weight269.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate CAS 401566-70-9 chemical structure

Description

The occurrence of Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate (CAS 401566-70-9), molecular formula C12H16ClN3O2 and molecular weight 269.73 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C12H16ClN3O2, Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 269.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H16ClN3O2
Molecular Weight269.73 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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