4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline CAS 401567-99-5
| CAS No. | 401567-99-5 |
| Molecular Formula | C13H13F3N4 |
| Molecular Weight | 282.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.26 g/mol gives 4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline (CAS 401567-99-5) is a high-purity analytical reference standard with the molecular formula C13H13F3N4 and a molecular weight of 282.26 g/mol.
4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline (C13H13F3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13F3N4 |
| Molecular Weight | 282.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Piperazin Standards
- 2-(Piperazin-1-yl)-3-(trifluoromethyl)quinoxaline (CAS 1095706-44-7)
- 5-(Piperazin-1-yl)-2-(trifluoromethyl)-1,6-naphthyridine (CAS 890302-17-7)
- 5-((6-(Piperazin-1-yl)pyrimidin-4-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-20-7)
- 2-(Piperazin-1-yl)benzo[d]oxazole-5-sulfonamide (CAS 1035840-39-1)
- 5-(Piperazin-1-ylsulfonyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 900641-20-5)
- (2-Methyl-6-(piperazin-1-yl)pyridin-3-yl)(phenyl)methanone (CAS 1355174-96-7)
- (4-Methyl-6-(piperazin-1-yl)pyridin-3-yl)(phenyl)methanone (CAS 1355182-13-6)
- 5-(Piperazin-1-ylsulfonyl)indolin-2-one (CAS 848369-76-6)
Recommended Standards
- 4-(Allyloxy)-5-methyl-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 318949-57-4)
- 4-(4-Ethylphenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 861439-49-8)
- 5-Amino-5-deoxyguanosine (CAS 4099-84-7)
- 3-Amino-3-deoxyguanosine (CAS 80015-76-5)
- 1,1'-(3,6-Dihydroxy-1,2-phenylene)bis(ethan-1-one) (CAS 39125-99-0)
- 2-(3-(Carboxymethyl)-4-(phenylthio)-phenyl)propanoic Acid (CAS 83237-49-4)
- 5-(1-Methylpyrrolidin-2-yl)-1H-indole (CAS 1355226-51-5)
- H-Glu(Trp-OH)-OH TFA Salt (CAS 66471-20-3（free base）)
- 2-(2-Amino-3-(difluoromethyl)pyridin-4-yl)acetonitrile (CAS 1805012-88-7)
- 2-Chloro-1,3,5-triazine (CAS 6153-86-2)
- 4-(Methylthio)quinoline (CAS 46000-25-3)
- tert-Butyl (2-amino-3-methylphenyl)carbamate (CAS 954238-92-7)
- Ethyl 2-(1-hydroxyethyl)thiazole-4-carboxylate (CAS 161891-80-1)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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