2-((2,4-Dichlorobenzyl)thio)pyrimidine-4,6-diamine CAS 401582-95-4
| CAS No. | 401582-95-4 |
| Molecular Formula | C11H10Cl2N4S |
| Molecular Weight | 301.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((2,4-Dichlorobenzyl)thio)pyrimidine-4,6-diamine (CAS 401582-95-4) is a high-purity analytical reference standard with the molecular formula C11H10Cl2N4S and a molecular weight of 301.19 g/mol.
The molecular framework of 2-((2,4-Dichlorobenzyl)thio)pyrimidine-4,6-diamine (C11H10Cl2N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2N4S |
| Molecular Weight | 301.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dichlorobenzyl Standards
- 2-((2,4-Dichlorobenzyl)thio)-6-methylpyrimidin-4-ol (CAS 91961-86-3)
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Recommended Standards
- 1-(7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (CAS 937591-29-2)
- 1-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-1(2H)-yl)ethanone (CAS 2170897-51-3)
- 2-(Pyrrolidin-1-yl)-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 2213446-70-7)
- 1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (CAS 937591-82-7)
- [6-(3,5-dimethyl-1h-pyrazol-1-yl)pyridin-3-yl]methanamine (CAS 1052564-18-7)
- (3-fluoro-1-methyl-1H-pyrrol-2-yl)methanamine (CAS 2167743-75-9)
- 4-(Chloromethyl)-2-methoxypyridine hydrochloride (CAS 193001-96-6)
- (4R)-4-(Difluoromethyl)-2,2-dimethyl-1,3-dioxolane (CAS 474329-39-0)
- 1-(3-Ethoxy-4-nitrophenyl)-4-piperidinol (CAS 1089283-25-9)
- Lubiprostone Impurity 11 (CAS CATO-C4X-113611)
- 5-(3,4-Dichlorophenyl)-4-methyl-4H-1,2,4-triazole-3-thiol 725217-53-8 8746AE C9H7Cl2N3S (CAS 725217-53-8)
- [5-Iodo-4-(1-methyl-piperidin-3-yl)-pyrimidin-2-yl]-dimethyl-amine (CAS 1361115-99-2)
- 3-(Chlorocarbonyl)phenyl Acetate (CAS 16446-73-4)
- KALA Amphipathic Peptide (CAS 187987-64-0)
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