5-Bromo-2-chloro-4-iodopyridine CAS 401892-47-5
| CAS No. | 401892-47-5 |
| Molecular Formula | C5H2BrClIN |
| Molecular Weight | 318.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-2-chloro-4-iodopyridine is closely related to a nitrile group, chlorine/bromine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-2-chloro-4-iodopyridine (CAS 401892-47-5), molecular formula C5H2BrClIN and molecular weight 318.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-chloro-4-iodopyridine (C5H2BrClIN) is characterized by a nitrile group, chlorine/bromine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-2-chloro-4-iodopyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2BrClIN |
| Molecular Weight | 318.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br/I-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-5-chloro-4-iodopyridine (CAS 1061357-88-7)
- 3-Bromo-5-chloro-4-iodopyridine (CAS 1070870-39-1)
- 2-Bromo-4-chloro-3-iodopyridine (CAS 1070870-41-5)
- 5-Bromo-3-chloro-2-iodopyridine (CAS 1159186-43-2)
- 2-Bromo-3-chloro-5-iodopyridine (CAS 1211525-78-8)
- 3-Bromo-6-chloro-2-iodopyridine (CAS 1211529-01-9)
- 2-Bromo-5-chloro-3-iodopyridine (CAS 1211535-24-8)
- 2-Bromo-6-chloro-3-iodopyridine (CAS 1211580-38-9)
Recommended Standards
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