1-(2-chloroethyl)-3-(trifluoromethyl)benZene CAS 402-35-7
| CAS No. | 402-35-7 |
| Molecular Formula | C9H8ClF3 |
| Molecular Weight | 208.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-chloroethyl)-3-(trifluoromethyl)benZene is closely related to fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(2-chloroethyl)-3-(trifluoromethyl)benZene (CAS 402-35-7), a certified reference material (molecular formula C9H8ClF3, MW 208.61 g/mol) for analytical method development and quality control.
1-(2-chloroethyl)-3-(trifluoromethyl)benZene (C9H8ClF3) contains fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-chloroethyl)-3-(trifluoromethyl)benZene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF3 |
| Molecular Weight | 208.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related chloroethyl Standards
- 1-(1-chloroethyl)-4-(trifluoromethyl)benzene (CAS 85289-90-3)
- 1-(2-chloroethyl)-2-(trifluoromethyl)benzene (CAS 94022-94-3)
- 1-(2-Chloroethyl)-4-(trifluoromethyl)benzene (CAS 85289-89-0)
- 2-(1-Chloroethyl)-3,4-dihydroquinazolin-4-one (CAS 137225-34-4)
- 3-(1-chloroethyl)-5-phenyl-1,2,4-oxadiazole (CAS 1595895-58-1)
- 2-(1-chloroethyl)-5-phenyl-1,3,4-oxadiazole (CAS 36770-21-5)
- 3-(2-Chloroethyl)-3,4-dihydroquinazolin-4-one (CAS 2940-68-3)
- 3-(2-Chloroethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 887582-84-5)
Recommended Standards
- 1-Chloro-2-(3,3,3-trifluoropropyl)benzene (CAS 96256-38-1)
- 4-Chloro-6-(pyridazin-4-yl)-1,3,5-triazin-2-amine (CAS 1566402-01-4)
- 1H-Pyrazolo[3,4-d]pyrimidine-3-carbonitrile, 6-amino-4-chloro-1-methyl- (CAS 2935432-21-4)
- 2-(2,2-Difluoroethoxy)ethane-1-sulfonyl chloride (CAS 1461707-60-7)
- N-Ethyl-3-methylbutan-1-amine (CAS 21035-52-9)
- 1,1,1-Trifluoromethanamine HCl (CAS 63689-56-5)
- L-2-Aminoadipic Acid (CAS 1118-90-7)
- (4-Octylbenzyl)triphenylphosphonium chloride (CAS 62640-29-3)
- 2-Amino-2-methylbutanoic acid (CAS 595-39-1)
- diphenyl [({[2-chloro-5-(trifluoromethyl)anilino]carbothioyl}amino)(2,4-dichlorophenyl)methyl]phosphonate (CAS 680214-52-2)
- N-(4,6-Dimethylpyrimidin-2-yl)-4-(trifluoromethyl)benzamide (CAS 497060-04-5)
- Teneligliptin impurity 57 (CAS CATO-C4X-176057)
- 3-Fluoro-5-(trifluoromethoxy)aniline (CAS 1352999-96-2)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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