1,3-Bis(trifluoromethyl)-benzene CAS 402-31-3
| CAS No. | 402-31-3 |
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Bis(trifluoromethyl)-benzene.
CATO supplies 1,3-Bis(trifluoromethyl)-benzene (CAS 402-31-3), a certified reference material (molecular formula C8H4F6, MW 214.11 g/mol) for analytical method development and quality control.
1,3-Bis(trifluoromethyl)-benzene (C8H4F6) contains fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 1,2-Bis(trifluoromethyl)benzene (CAS 433-95-4)
- 8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1020040-56-5)
- 2-(trifluoromethyl)imidazo[1,2-a]pyridine-8-carbaldehyde (CAS 1033434-50-2)
- 2-(Trifluoromethyl)-1H-benzo[d]imidazole-6-carbaldehyde (CAS 106429-45-2)
- 5-(Trifluoromethyl)-2H-indazole-7-carbaldehyde (CAS 1100212-67-6)
- 4-(Trifluoromethyl)-5-azaindole-3-carboxaldehyde (CAS 1190309-96-6)
- 6-(Trifluoromethyl)-1h-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190311-65-9)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1190315-73-1)
Recommended Standards
- 4,6-dichloro-1-(trideuteriomethyl)pyrazolo[3,4-d]pyrimidine (CAS 2570124-20-6)
- Dutasteride impurity G (CAS 433-19-2)
- (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid (CAS 4741-67-7)
- Vitamin Impurity 49 Sodium Salt (CAS CATO-C4X-177949)
- 2-(3-(4-Fluorophenyl)-1H-1,2,4-triazol-5-yl)aniline (CAS 104615-61-4)
- 4-Chloro-2-(6-methoxypyrimidin-4-yl)aniline (CAS 1802434-18-9)
- 2'-Methyl-[1,1'-biphenyl]-2-carbaldehyde (CAS 7111-68-4)
- N-(2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanesulfonamide (CAS 2246751-85-7)
- Ethyl 2-ethoxy-4-(2-methoxy-2-oxoethyl)benzoate (CAS 855868-68-7)
- 0099AF 4-Quinoxalin-2-yl-phenylamine 81622-74-4 C14H11N3 (CAS 81622-74-4)
- 2-Fluorobutane (CAS 359-01-3)
- Methyl 4-Formamidobenzoate (CAS 53405-05-3)
- 4-Iodo-1H-indazol-3-ol (CAS 885518-70-7)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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