(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester HCl CAS 40216-83-9

Purity >95%In StockPharmaceutical Standards
CAS No.40216-83-9
Molecular FormulaC6H11NO3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester HCl CAS 40216-83-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester HCl.

CATO supplies (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester HCl (CAS 40216-83-9), a certified reference material (molecular formula C6H11NO3HCl, MW 181.62 g/mol) for analytical method development and quality control.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester HCl is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H11NO3 HCl
Molecular Weight181.62 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1968
Halogen ContentCl-containing
Nitrogen Atoms1

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