Norethindrone Acetate Impurity 13 CAS 40228-41-9
| CAS No. | 40228-41-9 |
| Molecular Formula | C22H28Br2O4 |
| Molecular Weight | 516.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Norethindrone Acetate Impurity 13 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Norethindrone Acetate Impurity 13 (CAS 40228-41-9) is a high-purity analytical reference standard with the molecular formula C22H28Br2O4 and a molecular weight of 516.26 g/mol.
Structurally, Norethindrone Acetate Impurity 13 (C22H28Br2O4) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 516.26 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Norethindrone Acetate Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28Br2O4 |
| Molecular Weight | 516.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Br-containing |
Related Norethindrone Standards
- Norethindrone Impurity 27 (CAS 142154-46-9)
- Norethindrone 17-O-β-D-glucuronide (CAS 64701-11-7)
- Norethindrone Enanthate (CAS 3836-23-5)
- Norethindrone Impurity 11 (CAS CATO-C4X-171311)
- Norethindrone Diacetate (CAS 2205-78-9)
- Norethindrone Sulfate Sodium Salt (CAS 19778-24-6)
- Norethindrone Acetate EP Impurity I (CAS 50717-99-2)
- Norethindrone Acetate 6-alpha-Hydroxy Impurity (CAS 6856-28-6)
Recommended Standards
- 1,4,6,7-Tetrachloro-9,10-bis(phenylethynyl)anthracene (CAS 80034-20-4)
- 9,10-Bis(4-(bromomethyl)phenyl)anthracene (CAS 941703-52-2)
- 2,7-Dibromo-5,10-diphenyl-5,10-dihydroindolo[3,2-b]indole (CAS 1919062-54-6)
- 2-(2,6-dioxo-3-piperidyl)-4-[2-[2-(2-iodoethoxy)ethoxy]ethoxy]isoindoline-1,3-dione (CAS 2349356-56-3)
- 2-(Cyclohexylthio)-5-nitrobenzaldehyde (CAS 175278-46-3)
- 1-(Tetrahydrothiophen-3-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1707594-44-2)
- tert-Butyl (1-(4-methoxyphenyl)ethyl)carbamate (CAS 1321591-78-9)
- 2-(2-(Ethyl(isobutyl)amino)ethoxy)ethan-1-ol (CAS 1251114-07-4)
- 3,3-Dimethylhexahydro-1H-pyrrolo[1,2-c]imidazol-1-one (CAS 156171-63-0)
- (4-Aminopiperidin-1-yl)(4-chlorophenyl)methanone (CAS 676559-87-8)
- 3-(4-Chlorophenyl)-1H-indazol-5-amine (CAS 1181335-70-5)
- 5-(4-Amino-1h-pyrazol-1-yl)-2,2-dimethylpentanenitrile (CAS 1487282-76-7)
- 1,5-Dimethoxy-4,8-dinitronaphthalene (CAS 303777-47-1)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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