Norethindrone Impurity 27 CAS 142154-46-9
| CAS No. | 142154-46-9 |
| Molecular Formula | C28H36O6 |
| Molecular Weight | 468.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Norethindrone Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Norethindrone Impurity 27 (CAS 142154-46-9, C28H36O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Norethindrone Impurity 27 (C28H36O6) contains a steroid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C28H36O6 |
| Molecular Weight | 468.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
Related Norethindrone Standards
- Norethindrone Acetate Impurity 13 (CAS 40228-41-9)
- Norethindrone Enanthate (CAS 3836-23-5)
- Norethindrone Impurity 11 (CAS CATO-C4X-171311)
- Norethindrone Diacetate (CAS 2205-78-9)
- Norethindrone Sulfate Sodium Salt (CAS 19778-24-6)
- Norethindrone Acetate EP Impurity I (CAS 50717-99-2)
- Norethindrone Acetate 6-alpha-Hydroxy Impurity (CAS 6856-28-6)
- Norethindrone Acetate-2,2,4,6,6,10-d6 (Major) (CAS CATO-CCAD301458)
Recommended Standards
- 23,24,25,26-Tetranoroleana-1(10),3,5,7-tetraen-29-oic acid, 3,4,6-trihydroxy-9,13-dimethyl-2-oxo-, (9beta,13alpha,14beta,20alpha)- (CAS 1253387-35-7)
- Androstanediol-17g (CAS 148616-25-5)
- Fedratinib Impurity 6 (CAS 936091-39-3)
- endo-BCN-PEG3-NH-Boc (CAS 1807501-84-3)
- Itopride Impurity 1 (CAS 943518-63-6)
- Dexrazoxane Impurity 35 (CAS CATO-C4X-202035)
- Drotaverine Impurity 19 (CAS CATO-C4X-243519)
- Benzyl 1-(4-chlorophenyl)cyclopropylcarbamate (CAS 1215206-50-0)
- Methyl 2-(4-chlorophenyl)-4-oxo-4-(m-tolyl)butanoate (CAS 344281-20-5)
- 3-Bromo-4-fluorophenol (CAS 27407-11-0)
- Tert-butyl 7-iodo-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate (CAS 1973505-15-5)
- t-Butyl 4-(2-bromo-4-nitrophenoxy)piperidine-1-carboxylate (CAS 337520-16-8)
- 4-((N-(3,5-dichlorophenyl)methylsulfonamido)methyl)benzoic acid (CAS 1207326-90-6)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com