N-(4-fluorobenzyl)thiourea CAS 405-74-3
| CAS No. | 405-74-3 |
| Molecular Formula | C8H9FN2S |
| Molecular Weight | 184.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, N-(4-fluorobenzyl)thiourea is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-(4-fluorobenzyl)thiourea (CAS 405-74-3) is a high-purity analytical reference standard with the molecular formula C8H9FN2S and a molecular weight of 184.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-fluorobenzyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9FN2S |
| Molecular Weight | 184.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- S-(2-fluorobenzyl) ethanethioate (CAS 873463-80-0)
- S-(3-fluorobenzyl) ethanethioate (CAS 85582-63-4)
- 3-((2-Fluorobenzyl)oxy)propan-1-ol (CAS 873945-77-8)
- 2-((2-Fluorobenzyl)oxy)acetic acid (CAS 868277-75-2)
- 3-((3-Fluorobenzyl)amino)propan-1-ol (CAS 1038254-19-1)
- 2-((3-Fluorobenzyl)amino)propan-1-ol (CAS 1153894-68-8)
- 2-((4-Fluorobenzyl)amino)propan-1-ol (CAS 1154690-60-4)
- 3-((4-Fluorobenzyl)amino)propan-1-ol (CAS 161798-73-8)
Recommended Standards
- N-(3-fluoro-4-methylphenyl)thiourea (CAS 420130-45-6)
- Osmundacetone (CAS 37079-84-8)
- Methyl octahydro-1-benzofuran-2-carboxylate (CAS 2140305-77-5)
- Pinonic Acid (CAS 473-72-3)
- Phenylboronic Acid-d5 (CAS 215527-70-1)
- 2-Ethylbutyl 4-(2,5-dimethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 300360-11-6)
- 4-AMINO-2-(3-METHOXYPHENYL)-6,7-DIHYDRO-5H-CYCLOPENTA[D]PYRIMIDINE (CAS 1275675-85-8)
- 2-(5-(1,3-Dioxolan-2-yl)furan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1351353-51-9)
- Methyl 2-[4-(trifluoromethoxy)phenoxy]acetate (CAS 1403316-31-3)
- 2-(Chloromethyl)-4-phenylthiazole hydrochloride (CAS 1177287-80-7)
- 2-(6-Bromo-5-methyl-3H-imidazo[4,5-b]pyridin-2-yl)acetic acid (CAS 893723-46-1)
- 3-(2,3-Difluorophenoxy)pyrrolidine (CAS 1342666-89-0)
- Bazedoxifene Acetate Impurity 5 (CAS 328933-58-0)
- Semaglutide (CAS 910463-68-2（free base）)
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