Tenofovir disoproxil Impurity 76 CAS 40510-81-4
| CAS No. | 40510-81-4 |
| Molecular Formula | C3H5ClO3 |
| Molecular Weight | 124.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tenofovir disoproxil Impurity 76 (CAS 40510-81-4, C3H5ClO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tenofovir disoproxil Impurity 76 (C3H5ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 124.52 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir disoproxil Impurity 76 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H5ClO3 |
| Molecular Weight | 124.52 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 95 (CAS 58989-06-3)
- Tenofovir Impurity 114 (CAS 2227-98-7)
- Tenofovir disoproxil Impurity 40(Azathioprine EP Impurity F) (CAS 68-94-0)
- Tenofovir Impurity 90 (CAS 49622-08-4)
- Tenofovir disoproxil Impurity 56 (CAS 76483-21-1)
- Tenofovir disoproxil Impurity 136 (CAS CATO-C4X-1076136)
- Tenofovir disoproxil Impurity 92 (CAS 16606-55-6)
- Tenofovir disoproxil Impurity 94 (CAS 51260-39-0)
Recommended Standards
- (S)-3-Chloro-2-hydroxypropanoic acid (CAS 82079-44-5)
- β-Chlorolactic Acid (CAS 1713-85-5)
- (2R)-3-chloro-2-hydroxy-propanoic acid (CAS 61505-41-7)
- 2-Fluoro-2-methylpropanoyl chloride (CAS 140616-89-3)
- Moxifloxacin Impurity 43 (CAS 121577-35-3)
- Anastrozole Impurity 30 (CAS CATO-C4X-123930)
- Dapagliflozin impurity 214 (CAS CATO-C4X-1138214)
- Methyl 2-(3-(tert-butyl)thioureido)-3,3-dimethylbutanoate (CAS 1214138-23-4)
- Empagliflozin Impurity 98 (CAS CATO-C4X-106598)
- Gly-Gly-Gly-PEG4-methyltetrazine (CAS 2353409-82-0)
- N-(1-Isobutyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-3-(trifluoromethyl)benzamide (CAS 941991-52-2)
- Methyl 2-bromo-3-fluoro-4-nitrobenzoate (CAS 1805557-35-0)
- (1-Ethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanol dihydrochloride (CAS 1609403-67-9)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com