Tenofovir disoproxil Impurity 40(Azathioprine EP Impurity F) CAS 68-94-0

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.68-94-0
Molecular FormulaC5H4N4O
Molecular Weight136.11 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tenofovir disoproxil Impurity 40(Azathioprine EP Impurity F) CAS 68-94-0 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

As a process- or degradation-related impurity, Tenofovir disoproxil Impurity 40(Azathioprine EP Impurity F) (CAS 68-94-0, C5H4N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to an amide group, a hydroxyl group, an ether linkage, Tenofovir disoproxil Impurity 40(Azathioprine EP Impurity F) is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 136.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC5H4N4O
Molecular Weight136.11 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Nitrogen Atoms4

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