Benzylpenicillin Impurity 28 CAS 4052-54-4
| CAS No. | 4052-54-4 |
| Molecular Formula | C16H18N2O5S |
| Molecular Weight | 350.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Benzylpenicillin Impurity 28 (CAS 4052-54-4), a pharmacopoeial impurity reference standard (molecular formula C16H18N2O5S, MW 350.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Benzylpenicillin Impurity 28 (C16H18N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Benzylpenicillin Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O5S |
| Molecular Weight | 350.39 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzylpenicillin Standards
- Benzylpenicillin Impurity 10 (CAS 34104-15-9)
- Benzylpenicillin Potassium EP Impurity C (CAS 525-91-7)
- Benzylpenicillin Impurity 83 (CAS CATO-C4X-189983)
- Benzylpenicillin Impurity 84 (CAS CATO-C4X-189984)
- Benzylpenicillin Impurity 79 (CAS CATO-C4X-189979)
- Benzylpenicillin Potassium EP impurity E (CAS 11039-68-2)
- Benzylpenicillin Impurity 21(Mixture of Diastereomers) (CAS 13057-98-2)
- Benzylpenicillin EP Impurity E (CAS CATO-C4X-18995)
Recommended Standards
- Iguratimod Impurity 73 (CAS CATO-C4X-182673)
- Iguratimod Impurity 72 (CAS CATO-C4X-182672)
- Bumetanide Impurity 33 (CAS 28395-28-0)
- Iguratimod Impurity 150 (CAS CATO-C4X-1826150)
- Linagliptin impurity 141 (CAS CATO-C4X-1101141)
- Loxoprofen Impurity 130 (CAS 261521-19-1)
- Sunitinib Impurity 8 (CAS 251356-82-6)
- 2-Bromo-4-cyclopropoxy-N-methylnicotinamide (CAS 1243361-74-1)
- PBB No. 26 (CAS 59080-35-2)
- 5-Methyl-1-(2-(6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1174854-44-4)
- Calcium 3-hydroxybutanoate (CAS 586976-56-9)
- (S)-1-amino-2,3-dihydro-1H-indene-5-carbonitrile (CAS 903630-35-3)
- 2,2-Difluorospiro[2.3]Hexane-1-carboxylic acid (CAS 1936230-67-9)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com