Iguratimod Impurity 73 CAS CATO-C4X-182673
| CAS No. | CATO-C4X-182673 |
| Molecular Formula | C16H18N2O5S |
| Molecular Weight | 350.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Iguratimod Impurity 73 (CAS CATO-C4X-182673, C16H18N2O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Iguratimod Impurity 73 (C16H18N2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N2O5S |
| Molecular Weight | 350.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Iguratimod Standards
- Iguratimod Impurity 109 (CAS CATO-C4X-1826109)
- Iguratimod Impurity 131 (CAS CATO-C4X-1826131)
- Iguratimod Impurity 149 (CAS CATO-C4X-1826149)
- Iguratimod Impurity 150 (CAS CATO-C4X-1826150)
- Iguratimod Impurity 72 (CAS CATO-C4X-182672)
- Iguratimod Impurity 114 (CAS 123663-48-9)
- Iguratimod Impurity 64 (CAS CATO-C4X-182664)
- Iguratimod Impurity 51 (CAS CATO-C4X-182651)
Recommended Standards
- Benzylpenicillin Potassium EP Impurity C (CAS 525-91-7)
- Benzylpenicillin Impurity 28 (CAS 4052-54-4)
- Benzylpenicillin Impurity 83 (CAS CATO-C4X-189983)
- Benzylpenicillin Impurity 84 (CAS CATO-C4X-189984)
- Amiodarone Hydrochloride EP Impurity C (CAS 1397201-93-2)
- Fingolimod Hydrochloride EP Impurity B (CAS 162361-44-6)
- Oseltamivir Impurity 189 (CAS CATO-C4X-1720189)
- 4-(Cyclopropylmethoxy)piperidine (CAS 865106-51-0)
- (E)-3-(2-chlorophenyl)-N-(4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)acrylamide (CAS 873307-13-2)
- (E)-4-(4-Hydroxystyryl)pyridine (CAS 67882-97-7)
- 5-Chloro-2-(trifluoromethyl)benzamide (CAS 654-94-4)
- (S)-3-(Azetidin-2-ylmethoxy)pyridine (CAS 161416-98-4)
- Ethyl 2-(5-chloropentanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 331760-62-4)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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