2-(Thiophen-2-yl)ethane-1-sulfonyl chloride CAS 405308-14-7
| CAS No. | 405308-14-7 |
| Molecular Formula | C6H7ClO2S2 |
| Molecular Weight | 210.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Thiophen-2-yl)ethane-1-sulfonyl chloride (CAS 405308-14-7) is a high-purity analytical reference standard with the molecular formula C6H7ClO2S2 and a molecular weight of 210.70 g/mol.
Structurally, 2-(Thiophen-2-yl)ethane-1-sulfonyl chloride (C6H7ClO2S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 210.70 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7ClO2S2 |
| Molecular Weight | 210.70 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Thiophen Standards
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- 2-(4-(Thiophen-2-yl)piperidin-1-yl)ethan-1-amine (CAS 1268147-28-9)
- 1-[1-methyl-2-(thiophen-2-yl)piperidin-3-yl]methanamine (CAS 1343496-67-2)
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Recommended Standards
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- 2,4-Dimethylthiophene-3-sulfonyl chloride (CAS 208775-27-3)
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- [(2-Bromophenyl)methyl](prop-2-en-1-yl)amine hydrochloride (CAS 1240569-05-4)
- Vericiguat Impurity 19 (CAS 2112745-90-9)
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