3-Bromopyrrolidin-2-one CAS 40557-20-8
| CAS No. | 40557-20-8 |
| Molecular Formula | C4H6BrNO |
| Molecular Weight | 164.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromopyrrolidin-2-one.
3-Bromopyrrolidin-2-one (CAS 40557-20-8), molecular formula C4H6BrNO and molecular weight 164.00 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Bromopyrrolidin-2-one (C4H6BrNO) contains an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 164.00 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6BrNO |
| Molecular Weight | 164.00 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromopyrrolidin Standards
- 1-(3-Bromopyrrolidin-1-yl)ethan-1-one (CAS 1353989-43-1)
- (R)-1-(3-Bromopyrrolidin-1-yl)ethanone (CAS 1354016-98-0)
- (S)-1-(3-Bromopyrrolidin-1-yl)ethanone (CAS 1354020-79-3)
- 2-(3-Bromopyrrolidin-1-yl)acetic acid (CAS 1353959-48-4)
- 1-(3-Bromopyrrolidin-1-yl)-2-chloroethanone (CAS 1353947-31-5)
- 1-Benzyl-3-bromopyrrolidin-2-one (CAS 77868-84-9)
- 1-[(2S)-2-Bromopyrrolidin-1-yl]-2-(cyclopentylamino)ethan-1-one (CAS 1881275-85-9)
Recommended Standards
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- 2-(6-Chloro-4-(difluoromethyl)-5-methylpyridin-2-yl)acetonitrile (CAS 1806938-88-4)
- 4,6-Dibromo-2-(methylsulfonyl)pyrimidine (CAS 172899-12-6)
- Propyl stearate (CAS 3634-92-2)
- 5-Bromo-N-(4-methoxyphenyl)-2-pyridinamine (CAS 1220020-51-8)
- 1-Methyl-9H-pyrido[3,4-b]indol-6-ol (CAS 67767-19-5)
- N-Butyl-3-hydroxy-5-nitrobenzamide (CAS 1881289-46-8)
- Cholecystokinin Octapeptide (desulfated) (H-2070.0005) (CAS 198483-36-2)
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