1-Benzyl-3-bromopyrrolidin-2-one CAS 77868-84-9
| CAS No. | 77868-84-9 |
| Molecular Formula | C11H12BrNO |
| Molecular Weight | 254.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Benzyl-3-bromopyrrolidin-2-one (CAS 77868-84-9) is a high-purity analytical reference standard with the molecular formula C11H12BrNO and a molecular weight of 254.12 g/mol.
The molecular framework of 1-Benzyl-3-bromopyrrolidin-2-one (C11H12BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-Benzyl-3-bromopyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12BrNO |
| Molecular Weight | 254.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
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Recommended Standards
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- 1-[(2-Bromophenyl)methyl]pyrrolidin-2-one (CAS 756876-22-9)
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- 5-Methyl-4-(pyridin-4-yl)thiazol-2-amine (CAS 206555-50-2)
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- 3-chloro-4-(1H-indazol-1-yl)benzoic acid (CAS 1283004-89-6)
- Telmisartan EP Impurity J (CAS 885045-90-9)
- 4-Hydrazinobenzoic Acid-d4 Hydrochloride (CAS 1246816-67-0)
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