5-Bromo-2-(prop-2-yn-1-yloxy)pyridine CAS 406479-72-9
| CAS No. | 406479-72-9 |
| Molecular Formula | C8H6BrNO |
| Molecular Weight | 212.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Bromo-2-(prop-2-yn-1-yloxy)pyridine (CAS 406479-72-9), a certified reference material (molecular formula C8H6BrNO, MW 212.04 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-2-(prop-2-yn-1-yloxy)pyridine (C8H6BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Bromo-2-(prop-2-yn-1-yloxy)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrNO |
| Molecular Weight | 212.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-2-hydroxy-5-methylbenzonitrile (CAS 1032506-48-1)
- 2-Bromo-3-(hydroxymethyl)benzonitrile (CAS 1086429-88-0)
- 4-Bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-5-one (CAS 1114333-08-2)
- 6-Bromo-1H-indol-3-ol (CAS 114224-27-0)
- 4-Bromo-7-hydroxyindole (CAS 1167056-91-8)
- 2-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-5-one (CAS 1196154-12-7)
- 3-Bromo-6,7-Dihydro-5h-cyclopenta[B]pyridin-5-one (CAS 1196154-87-6)
- 4-Bromo-3-methoxybenzonitrile (CAS 120315-65-3)
Recommended Standards
- 5-Bromo-1-isoindolinone (CAS 552330-86-6)
- 5-Bromo-2-hydroxy-3-methylbenzonitrile (CAS 913191-20-5)
- 5-Bromo-1-(prop-2-yn-1-yl)pyridin-2(1H)-one (CAS 461661-76-7)
- 5-Bromo-2-methylbenzoxazole (CAS 5676-56-2)
- 3-(Methylamino)-3-phenylpropanamide (CAS 857936-78-8)
- 2-[2-(1,3-Benzoxazol-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione (CAS 623553-27-5)
- 2-(4-(Difluoromethyl)-3-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1804692-94-1)
- 2-(oxan-2-yl)propan-2-amine (CAS 1506878-85-8)
- Ambroxol Impurity 101 (CAS CATO-C4X-1085101)
- Ethyl 4-chloro-1-(3,5-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridazinecarboxylate (CAS 339030-94-3)
- 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 1169459-44-2)
- (S)-1-(3-bromo-5-fluoropyridin-2-yl)ethan-1-amine (CAS 1932587-71-7)
- 2,2-Dimethylsuccinic anhydride (CAS 17347-61-4)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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