Ambroxol Impurity 101 CAS CATO-C4X-1085101
| CAS No. | CATO-C4X-1085101 |
| Molecular Formula | C16H16Br2N2O3 |
| Molecular Weight | 444.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ambroxol Impurity 101 (CAS CATO-C4X-1085101), a pharmacopoeial impurity reference standard (molecular formula C16H16Br2N2O3, MW 444.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H16Br2N2O3, Ambroxol Impurity 101 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 444.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ambroxol Impurity 101 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16Br2N2O3 |
| Molecular Weight | 444.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol impurity 108 (CAS 73220-00-5)
- Ambroxol Impurity 87 (CAS CATO-C4X-108587)
- Ambroxol Impurity 91 (CAS CATO-C4X-108591)
- Ambroxol impurity 115 (CAS CATO-C4X-1085115)
- Ambroxol Impurity 90 (CAS CATO-C4X-108590)
- Ambroxol impurity 05 (CAS CATO-C4X-1085105)
- Ambroxol Impurity 93 (CAS CATO-C4X-108593)
- Ambroxol Impurity 96 (CAS CATO-C4X-108596)
Recommended Standards
- 2',5'-Dibromo-[1,1':4',1''-terphenyl]-4,4''-dicarbaldehyde (CAS 2375652-86-9)
- Perfluoro-3,6-dioxa-4-methyl-7-octene-1-sulfonic acid (CAS 29311-67-9)
- 1,4-Phenylenebis((4-bromophenyl)methanone) (CAS 52497-29-7)
- 4-(2,4-dinitrophenoxy)-3-iodo-5-methoxybenzaldehyde (CAS 792947-74-1)
- Mirogabalin Impurity 13 (CAS 1798817-68-1)
- Gadobutrol impurity 177 (CAS CATO-C4X-2120177)
- Ilaprazole Impurity 213 (CAS CATO-C4X-1130213)
- Chloro(phenyl)(trifluoromethyl)-l3-iodane (CAS 2204248-93-9)
- 4-Fluoro-2-(trifluoromethyl)pyridine (CAS 850246-04-7)
- 1-(4-Fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (CAS 221620-96-8)
- 1-(Adamantan-1-yl)-4-methylpyridin-1-ium (CAS 773043-32-6)
- 3,3-Difluorobutane-1-sulfonyl chloride (CAS 1785613-55-9)
- (2-Cyclohexylpyridin-4-yl)boronic acid (CAS 2225177-02-4)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com