Ribavirin Impurity 15 CAS 406680-61-3
| CAS No. | 406680-61-3 |
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ribavirin Impurity 15 (CAS 406680-61-3) is a certified pharmaceutical impurity reference standard with the molecular formula C7H6N4O2 and a molecular weight of 178.15 g/mol.
Structurally, Ribavirin Impurity 15 (C7H6N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 178.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Ribavirin Standards
- Ribavirin Impurity 16 (CAS 6034-68-0)
- Ribavirin Impurity 38 (CAS 5614-64-2)
- Ribavirin impurity 59 (CAS 18905-29-8)
- Ribavirin Impurity 60 (CAS 21733-05-1)
- Ribavirin Impurity 39 (CAS CATO-C4X-141339)
- Ribavirin Impurity 56 (CAS CATO-C4X-141356)
- Ribavirin Impurity 27 (CAS 1319257-87-8)
- Ribavirin Impurity 37 (CAS CATO-C4X-141337)
Recommended Standards
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- Allopurinol EP Impurity C (CAS 1346604-13-4)
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- Triamcinolone Acetonide Impurity 37 (CAS 72559-83-2)
- Ceritinib Impurity 18 (CAS CATO-C4X-1048918)
- Oxacillin Impurity 8 (CAS CATO-C4X-23218)
- 1-Bromo-4-(4-iodobutyl)benzene (CAS 330200-13-0)
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- 2-Bromo-1-(4-methylpiperidin-1-yl)propan-1-one (CAS 131580-55-7)
- 2-Bromo-3-chloro-5-fluorotoluene (CAS 1242339-16-7)
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