Ribavirin Impurity 16 CAS 6034-68-0
| CAS No. | 6034-68-0 |
| Molecular Formula | C7H7N5O |
| Molecular Weight | 177.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ribavirin Impurity 16 is closely related to an amide group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ribavirin Impurity 16 (CAS 6034-68-0, C7H7N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ribavirin Impurity 16 (C7H7N5O) contains an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 177.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ribavirin Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7N5O |
| Molecular Weight | 177.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 5 |
Related Ribavirin Standards
- Ribavirin Impurity 15 (CAS 406680-61-3)
- Ribavirin Impurity 38 (CAS 5614-64-2)
- Ribavirin impurity 59 (CAS 18905-29-8)
- Ribavirin Impurity 60 (CAS 21733-05-1)
- Ribavirin Impurity 39 (CAS CATO-C4X-141339)
- Ribavirin Impurity 56 (CAS CATO-C4X-141356)
- Ribavirin Impurity 27 (CAS 1319257-87-8)
- Ribavirin Impurity 37 (CAS CATO-C4X-141337)
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