Thiamine Impurity 36 CAS 408352-65-8

Purity ＞95%In StockPharmacopoeial Impurity Standards
CAS No.408352-65-8
Molecular FormulaC7H12N4
Molecular Weight152.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thiamine Impurity 36 CAS 408352-65-8 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Thiamine Impurity 36 (CAS 408352-65-8) is a certified pharmaceutical impurity reference standard with the molecular formula C7H12N4 and a molecular weight of 152.20 g/mol.

Owing to a nitrile group, an aromatic ring system, Thiamine Impurity 36 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 152.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC7H12N4
Molecular Weight152.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity＞95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms4

Related Thiamine Standards

Recommended Standards

Why CATO?