3,6-Dimethoxyphthalonitrile CAS 40904-87-8
| CAS No. | 40904-87-8 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3,6-Dimethoxyphthalonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3,6-Dimethoxyphthalonitrile (CAS 40904-87-8), molecular formula C10H8N2O2 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
3,6-Dimethoxyphthalonitrile (C10H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 2 |
Related Dimethoxyphthalonitrile Standards
Recommended Standards
- 3,6-Dihydroxy-2-naphthaldehyde (CAS 477727-36-9)
- 3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile (CAS 56053-56-6)
- 3-(Pyrazin-2-yloxy)phenol (CAS 72503-62-9)
- 3-Acetyl-1,6-naphthyridin-2(1H)-one, 97% (CAS 52816-63-4)
- (S)-1-(3-fluoro-5-methylphenyl)-2,2-dimethylpropan-1-amine (CAS 1390707-55-7)
- tert-Butyl 2,2,6-trimethylmorpholine-4-carboxylate (CAS 1488276-47-6)
- 5-Bromo-2-methylisonicotinonitrile (CAS 51454-48-9)
- 4-(Chloromethyl)-1-(methylsulfonyl)hexane (CAS 1496868-41-7)
- (R)-1-(2-fluoro-5-methoxyphenyl)ethan-1-amine (CAS 1213670-08-6)
- N-Methyl-2-oxo-N-phenylpropanamide (CAS 61110-50-7)
- 3-Bromo-5-cyclobutyl-1,2,4-oxadiazole (CAS 1359822-65-3)
- 3-Bromo-2,6-difluoro-benzenemethanamine (CAS 1499089-79-0)
- 3-Cyclopropoxy-6-ethyl-2-(methylthio)pyridine (CAS 1243375-87-2)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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