Ethyl 6-bromo-5-methoxy-1-methyl-2-(morpholinomethyl)-1H-indole-3-carboxylate CAS 40963-86-8
| CAS No. | 40963-86-8 |
| Molecular Formula | C18H23BrN2O4 |
| Molecular Weight | 411.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 6-bromo-5-methoxy-1-methyl-2-(morpholinomethyl)-1H-indole-3-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 6-bromo-5-methoxy-1-methyl-2-(morpholinomethyl)-1H-indole-3-carboxylate (CAS 40963-86-8) is a high-purity analytical reference standard with the molecular formula C18H23BrN2O4 and a molecular weight of 411.29 g/mol.
The molecular framework of Ethyl 6-bromo-5-methoxy-1-methyl-2-(morpholinomethyl)-1H-indole-3-carboxylate (C18H23BrN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 6-bromo-5-methoxy-1-methyl-2-(morpholinomethyl)-1H-indole-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H23BrN2O4 |
| Molecular Weight | 411.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- di-tert-Butyl 3-amino-6-bromo-1H-indole-1,2-dicarboxylate (CAS 2681278-24-8)
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- 4-{4-[(5-bromothiophen-2-yl)sulfonyl]piperazin-1-yl}-4-oxobutanoic acid (CAS 888111-57-7)
- Terbutaline impurity 102 (CAS CATO-C4X-1183102)
- Perindoprilat-13C3 (CAS CATO-CCAD302362)
- (S)-1-(4-Methoxyphenyl)-N-methylethanamine (CAS 20218-54-6)
- N-(4-Aminophenyl)-2-(pentyloxy)benzamide (CAS 1020054-01-6)
- 4-((Benzylamino)methyl)-2-methoxyphenol (CAS 69875-94-1)
- (E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine (CAS 477873-01-1)
- Benzyl 1-oxo-2,5-diazaspiro[3.4]octane-5-carboxylate (CAS 914389-34-7)
- Tert-butyl (1-(5-amino-2-fluorophenyl)ethyl)carbamate (CAS 1784380-52-4)
- (S)-2-(3-(N-Cyclopropylacetamido)pyrrolidin-1-yl)acetic acid (CAS 1354007-11-6)
- 3-tert-Butyl-6-methyl-3,4-dihydro-2H-1,4-benzoxazine (CAS 478048-77-0)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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