(E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine CAS 477873-01-1
| CAS No. | 477873-01-1 |
| Molecular Formula | C18H11Cl3F3N3O2 |
| Molecular Weight | 464.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine.
CATO supplies (E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine (CAS 477873-01-1), a certified reference material (molecular formula C18H11Cl3F3N3O2, MW 464.65 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 464.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-(1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethylidene)[(2,6-dichlorophenyl)methoxy]amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl3F3N3O2 |
| Molecular Weight | 464.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- n-(2-Chloro-6-iodo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)pivalamide (CAS 1357387-98-4)
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- 3-Chloro-N-(3-cyano-4-((3-(trifluoromethyl)phenyl)sulfonyl)phenyl)benzamide (CAS 477866-92-5)
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Recommended Standards
- Pristimerin (CAS 1258-84-0)
- 1,2-Bis(4-phenyl-5-(propylthio)-4H-1,2,4-triazol-3-yl)ethane (CAS 72743-90-9)
- Lancilactone C (CAS 218915-17-4)
- 4,4'-Diethyl-5,5'-bis(phenethylthio)-4H,4'H-3,3'-bi(1,2,4-triazole) (CAS 500267-41-4)
- Methyl 1-(cyclopropylmethyl)-4-oxocyclohexanecarboxylate (CAS 1391765-55-1)
- 3-(Tert-butyl)-4-(4-chlorophenyl)-N-(pyridin-3-ylmethyl)thiazol-2(3H)-imine (CAS 866009-98-5)
- (6-Chloro-2-(difluoromethyl)-5-fluoropyridin-3-yl)methanol (CAS 1805260-30-3)
- 1-(4-Bromo-2-fluorobenzyl)-1H-pyrazol-4-ol (CAS 1596023-38-9)
- Entrectinib Impurity 2 (CAS 1108745-33-0)
- 6-Chloro-pyridine-3-sulfonic acid dibenzylamide (CAS 568566-61-0)
- (2-Methoxy-1-methylethyl)(3-phenoxybenzyl)amine (CAS 423737-88-6)
- 1,3-Selenazolidine-4-carboxylic acid (CAS 63578-00-7)
- 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)-N-hydroxypicolinimidamide (CAS 155468-22-7)
- Angiotensin III Antipeptide (CAS 133605-55-7)
Why CATO?
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