2,2-Difluoro-1-(2-Furyl)-3-Hydroxy-4-Methyl-1-Pentanone CAS 410522-58-6
| CAS No. | 410522-58-6 |
| Molecular Formula | C10H12F2O3 |
| Molecular Weight | 218.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,2-Difluoro-1-(2-Furyl)-3-Hydroxy-4-Methyl-1-Pentanone (C10H12F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,2-Difluoro-1-(2-Furyl)-3-Hydroxy-4-Methyl-1-Pentanone (CAS 410522-58-6) is a high-purity analytical reference standard with the molecular formula C10H12F2O3 and a molecular weight of 218.20 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12F2O3 |
| Molecular Weight | 218.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 4',6-Difluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1176629-59-6)
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- 2',3'-Difluoro-[1,1'-biphenyl]-4-carbaldehyde (CAS 126163-38-0)
Recommended Standards
- 2,2-Difluoro-1-(2-Furyl)-3-Hydroxy-1-Hexanone (CAS 410522-52-0)
- 2,2-Difluoro-1-(3-Furyl)-3-Hydroxy-4-Methyl-1-Pentanone (CAS 334873-76-6)
- 2-(Trifluoromethyl)benzo[d]thiazol-7-amine (CAS 58460-22-3)
- 2,3-Difluorobenzophenone (CAS 208173-20-0)
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- tert-butyl 2-allylazepane-1-carboxylate (CAS 153749-94-1)
- 2-methoxy-2-methylpropanimidamide hydrochloride (CAS 619329-28-1)
- 2-(1-(Tert-butoxycarbonyl)azetidin-3-yl)-2,2-difluoroacetic acid (CAS 1781091-41-5)
- 3-[benzyl(methyl)amino]oxetane-3-carboxylic acid (CAS 2725791-24-0)
- (4-Methyl-2-(1H-pyrrol-1-yl)pyrimidin-5-yl)boronic acid (CAS 2225181-40-6)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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