5-Amino-4-hydroxyquinoline-2-carboxylic acid CAS 412035-88-2

Purity 97%+In StockPharmaceutical Standards
CAS No.412035-88-2
Molecular FormulaC10H8N2O3
Molecular Weight204.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-4-hydroxyquinoline-2-carboxylic acid CAS 412035-88-2 chemical structure

Description

The occurrence of 5-Amino-4-hydroxyquinoline-2-carboxylic acid is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Amino-4-hydroxyquinoline-2-carboxylic acid (CAS 412035-88-2), molecular formula C10H8N2O3 and molecular weight 204.18 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 5-Amino-4-hydroxyquinoline-2-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Amino-4-hydroxyquinoline-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8N2O3
Molecular Weight204.18 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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