Etoricoxib Impurity 45 CAS 855307-80-1
| CAS No. | 855307-80-1 |
| Molecular Formula | C18H13ClN2O2S |
| Molecular Weight | 356.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Etoricoxib Impurity 45 (CAS 855307-80-1), a pharmacopoeial impurity reference standard (molecular formula C18H13ClN2O2S, MW 356.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Etoricoxib Impurity 45 (C18H13ClN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Etoricoxib Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClN2O2S |
| Molecular Weight | 356.83 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 44 (CAS 855307-79-8)
- Etoricoxib Impurity 86 (CAS CATO-C4X-108086)
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- Etoricoxib Impurity 47 (CAS CATO-C4X-108047)
- Etoricoxib D3 (CAS 850896-71-8)
- Etoricoxib D4 (CAS 1131345-14-6)
- Etoricoxib Impurity 7 (CAS CATO-C4X-10807)
- Etoricoxib Impurity 8 (CAS 646459-39-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com