5-(Hydroxymethyl)pyrazine-2-carboxamide CAS 412277-94-2
| CAS No. | 412277-94-2 |
| Molecular Formula | C6H7N3O2 |
| Molecular Weight | 153.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Hydroxymethyl)pyrazine-2-carboxamide (CAS 412277-94-2) is a high-purity analytical reference standard with the molecular formula C6H7N3O2 and a molecular weight of 153.14 g/mol.
5-(Hydroxymethyl)pyrazine-2-carboxamide (C6H7N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(Hydroxymethyl)pyrazine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7N3O2 |
| Molecular Weight | 153.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Hydroxymethyl Standards
- 6-(Hydroxymethyl)picolinic acid (CAS 1197-10-0)
- 5-(Hydroxymethyl)nicotinic acid (CAS 1240620-76-1)
- 2-(Hydroxymethyl)isonicotinic acid (CAS 915140-06-6)
- 2-(Hydroxymethyl)nicotinic acid (CAS 81113-14-6)
- 3-(Hydroxymethyl)isonicotinic acid (CAS 81113-13-5)
- 3-(Hydroxymethyl)picolinic acid (CAS 875256-15-8)
- 3-(Hydroxymethyl)pyrazine-2-carboxamide (CAS 40108-00-7)
- 4-(Hydroxymethyl)nicotinic acid (CAS 72726-63-7)
Recommended Standards
- 5-(Hydroxymethyl)picolinic acid (CAS 39977-41-8)
- 5,6,7,8-Tetrahydro-4H-[1,2,5]oxadiazolo[3,4-c]azepin-4-one (CAS 330982-36-0)
- 5-(Aminomethyl)pyrimidine-2-carboxylic acid (CAS 76196-72-0)
- 5,6-Diaminonicotinic acid (CAS 267875-45-6)
- tert-Butyl (2,6-difluoropyridin-3-yl)carbamate (CAS 1334646-77-3)
- (3-Chloro-4-propoxyphenyl)methanol (CAS 944441-69-4)
- 3-(5-Ethyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride (CAS 1707580-46-8)
- (6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1,2:1,5]pyrrolo[2,3-d]pyridazine-4-carboxam (CAS 870005-19-9)
- Sodium 2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-8-methylquinoline-6-sulfonate (CAS 83929-58-2)
- 5-Chloro-4-methyl-2-(o-tolyl)pyridine (CAS 2635937-69-6)
- Benzylpenicillin Impurity 10 (CAS 34104-15-9)
- 4-Hydroxy-5-methyl-2,3-dihydro-1H-inden-1-one (CAS 1092553-17-7)
- (8-chloro-1-naphthyl)boronic acid (CAS 2305022-53-9)
- Neuropeptide AF (human) (CAS 192387-38-5)
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