3-Chloro-6-hydroxy-2-nitrobenzaldehyde CAS 412336-53-9
| CAS No. | 412336-53-9 |
| Molecular Formula | C7H4ClNO4 |
| Molecular Weight | 201.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Chloro-6-hydroxy-2-nitrobenzaldehyde (CAS 412336-53-9), a certified reference material (molecular formula C7H4ClNO4, MW 201.56 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-Chloro-6-hydroxy-2-nitrobenzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClNO4 |
| Molecular Weight | 201.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-hydroxy-3-nitrobenzaldehyde (CAS 16634-90-5)
- 2-Chloro-6-hydroxy-3-nitrobenzaldehyde (CAS 38226-05-0)
- 2-Chloro-6-nitrobenzoic acid (CAS 5344-49-0)
- 3-chloro-2-nitrobenzoic acid (CAS 4771-47-5)
- 3-Chloro-4-hydroxy-5-nitrobenzaldehyde (CAS 98555-61-4)
- 3-Chloro-4-nitrobenzoic acid (CAS 39608-47-4)
- 4-Chloro-2,6-pyridinedicarboxylic Acid (CAS 4722-94-5)
- 4-chloro-2-nitrobenzoic acid (CAS 6280-88-2)
Recommended Standards
- 3-Hydroxy-4-nitrobenzoyl chloride (CAS 36852-58-1)
- 2-Nitrophenyl Chloroformate (CAS 50353-00-9)
- 4-Chloro-5-hydroxy-2-nitrobenzaldehyde (CAS 873983-83-6)
- 2-Hydroxy-5-nitrobenzoyl chloride (CAS 3223-20-9)
- N-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((4-chlorophenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 895646-86-3)
- Ethyl 2-(3-(3-methoxyphenyl)cyclobutyl)acetate (CAS 2114272-54-5)
- 2-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 228107-82-2)
- 1-[[2-[(1S)-1-Aminoethyl]-4-oxazolyl]carbonyl]-L-prolyl-L-isoleucine (CAS 647011-19-6)
- 4-Hydroxy-3’-methylbenzophenone (CAS 71372-37-7)
- 5-Bromo-N-isopropylpyridin-3-amine (CAS 1201643-57-3)
- (S)-2,2'-((2-(2-Carboxypyrrolidin-1-yl)-2-oxoethyl)azanediyl)diacetic acid (CAS 93583-08-5)
- Forestine (CAS 91794-14-8)
- 4-(ethylsulphonyl)-2-nitrophenol 4-Ethylsulfonyl-2-nitrophenol 84996-11-2 (CAS 84996-11-2)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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