Fluconazole Impurity 43 CAS 41253-21-8
| CAS No. | 41253-21-8 |
| Molecular Formula | C2H2N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluconazole Impurity 43.
As a process- or degradation-related impurity, Fluconazole Impurity 43 (CAS 41253-21-8, C2H2N3Na) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, Fluconazole Impurity 43 is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 91.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Fluconazole Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C2H2N3 Na |
| Molecular Weight | 91.05 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 3 |
Related Fluconazole Standards
- Fluconazole-d4 (CAS 1124197-58-5)
- Fluconazole EP Impurity F (CAS 118689-07-9)
- Fluconazole Impurity 48 (CAS 1222655-38-0)
- Fluconazole Impurity 58 (CAS 123091-15-6 (free base))
- Fluconazole Impurity 19 (CAS 1348664-75-4)
- Fluconazole β-D-glucuronide (CAS 136134-23-1)
- Fluconazole EP Impurity I Bromide (CAS 150168-54-0)
- Fluconazole EP Impurity H (CAS 150194-52-8)
Recommended Standards
- Ruxolitinib Impurity 187 (CAS CATO-C4X-2058187)
- Baxdrostat Impurity 32 (CAS 1428651-98-2)
- Mivacurium chloride Impurity 53 (CAS CATO-C4X-137553)
- 3'-(Benzyloxy)[1,1'-biphenyl]-3-carbaldehyde (CAS 893736-16-8)
- 3-(4,4,5,5-Tetraethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2769970-49-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-cyclopropylthiophen-2-yl)boronate (CAS 2223033-79-0)
- Ceftazidime Impurity 53 (CAS CATO-C4X-121253)
- 2-Bromo-2-methyl-N-(2-methyl-5-nitrophenyl)propanamide (CAS 1770517-01-5)
- 2-chloro-6-{5H,6H,7H,8H-imidazo[1,2-a]pyrazin-7-yl}pyridine-4-carboxylic acid (CAS 1284159-82-5)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
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