2-(Chloromethyl)-5-ethoxy-1,3,4-thiadiazole CAS 4153-74-6
| CAS No. | 4153-74-6 |
| Molecular Formula | C5H7ClN2OS |
| Molecular Weight | 178.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Chloromethyl)-5-ethoxy-1,3,4-thiadiazole (CAS 4153-74-6) is a high-purity analytical reference standard with the molecular formula C5H7ClN2OS and a molecular weight of 178.64 g/mol.
Based on its molecular formula C5H7ClN2OS, 2-(Chloromethyl)-5-ethoxy-1,3,4-thiadiazole contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 178.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN2OS |
| Molecular Weight | 178.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-(2-chloroethyl)-5-methoxy-1,3,4-thiadiazole (CAS 84353-08-2)
- 2-Chloro-1-(2-thioxoimidazolidin-1-yl)ethanone (CAS 64202-34-2)
- 5-chloro-3-(1-methoxyethyl)-1,2,4-thiadiazole (CAS 1506875-62-2)
- 2-Chloro-N-(4,5-dihydrothiazol-2-yl)acetamide (CAS 80650-47-1)
- Ethyl 2-amino-6-fluorobenzoate (CAS 1108668-11-6)
- Imidazo[1,5-a]pyrazine (CAS 274-49-7)
- 6-Oxo-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylic acid (CAS 1041430-01-6)
- 2,4,4-Trimethylpentane-1,3-diyl bis(2-methylpropanoate) (CAS 74381-40-1)
- Lamivudine-13C-15N2 (CAS 134678-17-4 (unlabelled))
- 1-(5-Bromoindol-1-yl)ethanone (CAS 61995-52-6)
- Vamidothion-Sulfoxide (CAS 20300-00-9)
- 3-formyl-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid (CAS 1190316-06-3)
- N-(4-methoxybenzyl)-2,2,6,6-tetramethylpiperidin-4-amine (CAS 447455-77-8)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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