Flurbiprofen impurity 122 CAS 41635-83-0
| CAS No. | 41635-83-0 |
| Molecular Formula | C16H15FO3 |
| Molecular Weight | 274.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Flurbiprofen impurity 122.
CATO supplies Flurbiprofen impurity 122 (CAS 41635-83-0), a pharmacopoeial impurity reference standard (molecular formula C16H15FO3, MW 274.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Flurbiprofen impurity 122 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15FO3 |
| Molecular Weight | 274.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 26 (CAS 64858-90-8)
- Flurbiprofen Impurity 106 (CAS 61467-10-5)
- Flurbiprofen Impurity 38 (CAS CATO-C4X-144438)
- Flurbiprofen impurity 102 (CAS CATO-C4X-1444102)
- Flurbiprofen Impurity 88 (CAS 1915720-16-9)
- Flurbiprofen Impurity 17 (CAS 78543-08-5)
- Flurbiprofen Impurity 27 (CAS CATO-C4X-144427)
- Flurbiprofen Impurity 58 (CAS CATO-C4X-144458)
Recommended Standards
- Pidotimod Impurity 13 (CAS CATO-C4X-107813)
- Propofol Impurity 55 (CAS CATO-C4X-147355)
- N,N-Diethyl-4-hydroxy-3-nitrobenzenesulfonamide (CAS 54964-07-7)
- Propofol Impurity 56 (CAS CATO-C4X-147356)
- Citalopram Impurity 75 (CAS CATO-C4X-110975)
- Abiraterone Impurity 27 (CAS 154229-21-7)
- Dacomitinib Impurity 17 (CAS CATO-C4X-208617)
- tert-Butyl 4-((1R,2R)-1-(4-chlorophenyl)-1-hydroxypentan-2-yl)benzoate (CAS 1215767-71-7)
- 5-(Methylthio)-4H-thieno[3,2-b]pyrrole (CAS 102788-09-0)
- 1-(3-Nitroquinolin-4-yl)guanidine (CAS 51294-35-0)
- 2-iodo-4-(methylsulfanyl)benzonitrile (CAS 54558-83-7)
- 1-Isobutyl-3-methyl-6-thioxodihydropyrimidine-2,4(1H,3H)-dione (CAS 216686-76-9)
- (E)-4-oxo-4-((4-(trifluoromethoxy)phenyl)amino)but-2-enoic acid (CAS 298217-69-3)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com