Fenofibrate Impurity 22 CAS 41806-25-1
| CAS No. | 41806-25-1 |
| Molecular Formula | C14H11ClO2 |
| Molecular Weight | 246.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Fenofibrate Impurity 22 (CAS 41806-25-1, C14H11ClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fenofibrate Impurity 22 (C14H11ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 246.69 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClO2 |
| Molecular Weight | 246.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
Related Fenofibrate Standards
- Fenofibrate Impurity 19 (CAS 10547-60-1)
- Fenofibrate Impurity 15 (CAS CATO-C4X-164315)
- Fenofibrate Impurity N3 (CAS 1871-38-1)
- Fenofibrate Impurity 5 (CAS 62810-39-3)
- Fenofibrate Impurity 7 (CAS 61002-52-6)
- Fenofibrate Impurity N1 (CAS 55270-71-8)
- Fenofibrate Impurity 14 (CAS 60013-02-7)
- Fenofibrate Impurity 15 (CAS 34183-01-2)
Recommended Standards
- Chlorphenamine Impurity 26 (CAS CATO-C4X-118826)
- 61535-46-4 3-(Benzyloxy)benzoyl chloride DTXSID20407350 (CAS 61535-46-4)
- 4-Chloro-3-methoxybenzophenone (CAS 32363-45-4)
- 42973-13-7 (Biphenyl-4-yloxy)acetyl chloride MFCD11107993 (CAS 42973-13-7)
- Rasagiline Impurity 33 (CAS CATO-C4X-191333)
- Sertraline Impurity 29 (CAS 36159-73-6)
- Empagliflozin Impurity 165 (CAS CATO-C4X-1065165)
- Sodium phosphate monohydrate (CAS 10049-21-5)
- Fenpropimorph-d3 (CAS 1292815-71-4)
- 3-Chloro-7-methyl-7,8-dihydroquinolin-5(6H)-one (CAS 103968-50-9)
- 3-(1-Adamantyl)-4-hydroxy-5-methoxybenzoic acid (CAS 893784-49-1)
- 4-Chlorophenyl-2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside (CAS 5041-92-9)
- (2S-cis)-4-[(Triphenylmethyl)thio]-1,2-Pyrrolidinedicarboxylic Acid 2-methyl 1-[(4-nitrophenyl)methyl] Ester (CAS 147117-72-4)
- C-Peptide（dog） (CAS 39016-05-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com