Sertraline Impurity 29 CAS 36159-73-6
| CAS No. | 36159-73-6 |
| Molecular Formula | C16H13ClO |
| Molecular Weight | 256.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sertraline Impurity 29 is closely related to a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Sertraline Impurity 29 (CAS 36159-73-6), a pharmacopoeial impurity reference standard (molecular formula C16H13ClO, MW 256.73 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sertraline Impurity 29 (C16H13ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClO |
| Molecular Weight | 256.73 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Sertraline Standards
- Sertraline Impurity 69 (CAS CATO-C4X-134469)
- Sertraline Impurity 71 (CAS CATO-C4X-134471)
- Sertraline Impurity 75 (CAS CATO-C4X-134475)
- Sertraline Impurity 46 (CAS CATO-C4X-134446)
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Impurity 45 (CAS CATO-C4X-134445)
- Sertraline EP Impurity D (1S, 4S-Isomer) (CAS 871838-58-3)
- Sertraline EP Impurity B (CAS 52758-03-9)
Recommended Standards
- (4-chlorophenyl)(2-phenylcyclopropyl)methanone 338415-82-0 KS-0000368O (CAS 338415-82-0)
- tert-Butyl 4-amino-2-chlorobenzylcarbamate (CAS 400720-72-1)
- Metoclopramide Impurity 125 (CAS 476615-04-0)
- tert-Butyl (3-amino-5-chloro-2-methylphenyl)carbamate (CAS 2113623-42-8)
- Linezolid Impurity 115 (CAS CATO-C4X-1073115)
- Arotinolol Impurity 29 (CAS CATO-C4X-185429)
- Itraconazole Impurity 97 (CAS CATO-C4X-149797)
- 3-Isopropyl-5-(1-(pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazole (CAS 1713639-28-1)
- N-(2,3-dichlorobenzyl)-N-isopropylglycine (CAS 1353963-90-2)
- rel-(Benzyl (3R,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate) (CAS 913574-96-6)
- (2-(m-tolyl)thiazol-4-yl)methanamine 89152-85-2 C-(2-M-TOLYL-THIAZOL-4-YL)-METHYLAMINE (CAS 89152-85-2)
- 2-(1H-Pyrrol-1-yl)benzoyl chloride (CAS 133662-28-9)
- 4-(Allylamino)-2,6-diphenylpyrimidine-5-carbonitrile (CAS 320418-31-3)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com