5-Fluoro-4-hydroxypyridin-2(1H)-one CAS 41935-70-0
| CAS No. | 41935-70-0 |
| Molecular Formula | C5H4FNO2 |
| Molecular Weight | 129.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoro-4-hydroxypyridin-2(1H)-one.
5-Fluoro-4-hydroxypyridin-2(1H)-one (CAS 41935-70-0) is a high-purity analytical reference standard with the molecular formula C5H4FNO2 and a molecular weight of 129.09 g/mol.
Structurally, 5-Fluoro-4-hydroxypyridin-2(1H)-one (C5H4FNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 129.09 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-4-hydroxypyridin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4FNO2 |
| Molecular Weight | 129.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-6-hydroxypyridin-2(1H)-one (CAS 1296176-85-6)
- 5-fluoro-4-imino-1,2,3,4-tetrahydropyrimidin-2-one (CAS 130256-61-0)
- 4-Fluoro-4-methyl-3-oxopentanenitrile (CAS 1188907-26-7)
- 2-(4-Fluoro-1H-pyrazol-1-yl)ethanamine (CAS 1174306-39-8)
- 8-Fluoro-3-azabicyclo[3.2.1]octane (CAS 1341039-59-5)
- 3-Fluoro-8-azabicyclo[3.2.1]octane (CAS 1404286-36-7)
- 6-Fluoro-2-azaspiro[3.4]octane (CAS 1638920-40-7)
- 8-Fluoro-5-azaspiro[2.5]Octane (CAS 1779808-59-1)
Recommended Standards
- 5-amino-3-fluoropyrazin-2(1H)-one (CAS 500148-37-8)
- 6-Fluorocytosine (CAS 2193-47-7)
- 2-Cyano-1-fluorocyclopropane-1-carboxylic acid (CAS 2168031-08-9)
- 5-Fluorocytosine (CAS 2022-85-7)
- (6-(2-Methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanamine (CAS 1708288-32-7)
- IDIC (CAS 1883441-92-6)
- 4-Chloro-2-cyclopropoxybenzaldehyde (CAS 1243480-49-0)
- 5-Methyl-2-oxo-1,3-dioxolane-4-carbonitrile (CAS 827300-18-5)
- 3,5-Dichloro-N-{[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}-N-(4-methoxyphenyl)benzene-1-sulfonamide (CAS 957041-52-0)
- ethyl 5-chloro-7-oxo-4H-pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 2394830-31-8)
- 4-Chloro-2-methyl-3-pyridinecarbonitrile (CAS 1261487-92-6)
- Fmoc-(S)-3-Amino-3-(2,3-dichlorophenyl)-propionic acid (CAS 501015-35-6)
- 3-Chloro-2-(1H-pyrrol-1-yl)benzonitrile (CAS 866042-71-9)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com