2-Cyano-1-fluorocyclopropane-1-carboxylic acid CAS 2168031-08-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2168031-08-9
Molecular FormulaC5H4FNO2
Molecular Weight129.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyano-1-fluorocyclopropane-1-carboxylic acid CAS 2168031-08-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Cyano-1-fluorocyclopropane-1-carboxylic acid.

2-Cyano-1-fluorocyclopropane-1-carboxylic acid (CAS 2168031-08-9) is a high-purity analytical reference standard with the molecular formula C5H4FNO2 and a molecular weight of 129.09 g/mol.

2-Cyano-1-fluorocyclopropane-1-carboxylic acid (C5H4FNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Cyano-1-fluorocyclopropane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H4FNO2
Molecular Weight129.09 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

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