Tramadol EP Impurity E HCl CAS 42036-65-7
| CAS No. | 42036-65-7 |
| Molecular Formula | C9H17NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tramadol EP Impurity E HCl is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Tramadol EP Impurity E HCl (CAS 42036-65-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H17NOHCl and a molecular weight of 191.70 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tramadol EP Impurity E HCl is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tramadol EP Impurity E HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17NO HCl |
| Molecular Weight | 191.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tramadol Standards
- (+)-Tramadol-D6 Hydrochloride (CAS 1109217-84-6)
- Tramadol-d6 HCl (N,N-dimethyl-d6) (mixture of diastereomers) (CAS 1189374-50-2)
- (-)-Tramadol (CAS 123134-25-8)
- Tramadol N-Oxide (CAS 147441-56-3)
- (-)-Tramadol Hydrochloride (CAS 148229-79-2)
- Tramadol EP Impurity A (CAS 152538-36-8)
- Tramadol Impurity 2 (CAS 187219-95-0)
- Tramadol Impurity 1 (CAS 1884-42-0)
Recommended Standards
- Etrasimod Impurity 61 (CAS CATO-C4X-321461)
- Ampicillin Impurity 31 (CAS CATO-C4X-144331)
- Metoclopramide Impurity 111 (CAS CATO-C4X-1415111)
- 6-Formylpicolinonitrile (CAS 85148-95-4)
- [4,4'-Bipyridine] 1-oxide (CAS 39182-30-4)
- (S)-2-Amino-1-((S)-2-((dimethylamino)methyl)pyrrolidin-1-yl)propan-1-one (CAS 1401665-87-9)
- 2-Bromo-5-cyano-3-formylbenzenesulfonyl chloride (CAS 1805485-65-7)
- 4-Bromo-n-ethoxy-2-fluorobenzamide (CAS 1147338-05-3)
- 2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one (CAS 1313399-38-0)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
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