6-Fluoro-2-methylquinolin-5-ol CAS 420786-95-4
| CAS No. | 420786-95-4 |
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoro-2-methylquinolin-5-ol.
6-Fluoro-2-methylquinolin-5-ol (CAS 420786-95-4) is a high-purity analytical reference standard with the molecular formula C10H8FNO and a molecular weight of 177.18 g/mol.
Structurally, 6-Fluoro-2-methylquinolin-5-ol (C10H8FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 177.18 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoro-2-methylquinolin-5-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-2-(1h-pyrazol-1-yl)aniline (CAS 1006960-35-5)
- 7-Fluoro-2-methylquinazolin-4-amine (CAS 1009036-30-9)
- 3-(3-Fluoro-4-methylphenyl)-3-oxopropanenitrile (CAS 1016770-89-0)
- 6-FLUORO-7-METHOXY-ISOQUINOLINE (CAS 1036711-00-8)
- 8-Fluoro-4-methylisoquinolin-1(2H)-one (CAS 1050203-45-6)
- 6-Fluoro-8-methylquinolin-4-ol (CAS 1065092-74-1)
- 7-Fluoro-8-methylquinolin-4-ol (CAS 1065092-79-6)
- 6-Fluoro-8-hydroxy-2-methylquinoline (CAS 1070897-08-3)
Recommended Standards
- 6-Fluoro-2-methylquinolin-4(1H)-one (CAS 389635-71-6)
- 6-Fluoro-3-methylquinolin-4-ol (CAS 442-09-1)
- 6-Fluoro-2-methyl-1H-indole-3-carbaldehyde (CAS 933747-88-7)
- 6-Fluoro-4-hydrazinylquinoline (CAS 49612-09-1)
- 4-(1,3-Dioxan-2-yl)phenol (CAS 6052-80-8)
- 4-Bromo-2-pyrrolidinobenzoic Acid (CAS 1099609-12-7)
- 2,6-Dimethyl-4-nitropyridine (CAS 4913-57-9)
- 3-Methyl Isonicotinic Acid-d6 (CAS 1346599-31-2)
- Big Endothelin-2 (1-37), human (CAS 132699-72-0)
- 4-(5-(3-Nitrobenzylidene)cyclopent-1-en-1-yl)morpholine (CAS 588699-53-0)
- 1-(2-Methoxyphenyl)-N-methylethanamine hydrochloride (CAS 1269036-30-7)
- 4-(2-Bromoethoxy)-1,2-dimethylbenzene (CAS 3351-53-9)
- 2-Bromo-6-methylbenzene-1,4-diol (CAS 50848-60-7)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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